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Note: Actual product
may differ from
the image above

Other brand names of Cymbalta are duloxetine hydrochloride.

Why do some drugs have different names?
These are trade or brand names registered by the manufacturer. In different countries manufacturers will often use different trade names. The medications have the same active ingredients, but may look different and have a different trade name.

What is Cymbalta?
Cymbalta (duloxetine) is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). It affects chemicals in the brain that may become unbalanced and cause depression.

Cymbalta is used to treat major depressive disorder and general anxiety disorder.

Cymbalta is also used to treat fibromyalgia (a chronic pain disorder), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain).

Cymbalta is also used to treat pain caused by nerve damage in people with diabetes (diabetic neuropathy).

Cymbalta may also be used for purposes not listed in this medication guide.

Important information about Cymbalta
Do not use Cymbalta if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. After you stop taking Cymbalta, you must wait at least 5 days before you start taking an MAOI.

Treatments for depression are getting better everyday and there are things you can start doing right away.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Avoid drinking alcohol while taking Cymbalta. It may increase your risk of liver damage.

Before taking Cymbalta
Do not use Cymbalta if you are allergic to duloxetine, or if you have untreated or uncontrolled glaucoma.

Do not use Cymbalta if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. After you stop taking Cymbalta, you must wait at least 5 days before you start taking an MAOI.

To make sure Cymbalta is safe for you, tell your doctor if you have:
- liver or kidney disease;
- seizures or epilepsy;
- a bleeding or blood clotting disorder;
- high blood pressure;
- glaucoma;
- bipolar disorder (manic depression);
- a history of drug abuse or suicidal thoughts; or
- if you are being treated with methylene blue injection.
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Cymbalta. Your family or other caregivers should also be alert to changes in your mood or symptoms.

FDA pregnancy category C. It is not known whether Cymbalta will harm an unborn baby. However, Cymbalta may cause problems in a newborn if you take the medicine during the third trimester of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Cymbalta on the baby.

Duloxetine can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking this medication.

Older adults may be more sensitive to the side effects of this medication.

Do not give Cymbalta to a child without medical advice.

How Cymbalta Is Believed to Work
Cymbalta is indicated for the treatment of major depressive disorder (MDD). The efficacy of Cymbalta was established in four short-term trials and one maintenance trial in adults.

Cymbalta is indicated for the treatment of generalized anxiety disorder (GAD). The efficacy of Cymbalta was established in three short-term trials and one maintenance trial in adults.

Cymbalta is indicated for the management of diabetic peripheral neuropathic pain and fibromyalgia.

Cymbalta is indicated for the management of chronic musculoskeletal pain due to chronic osteoarthritis pain and chronic low back pain.

Cymbalta is a non-narcotic, non-NSAID, non-addictive, once-a-day, FDA-approved treatment.

Although the exact way that Cymbalta works in people is unknown, it is believed to be related to an increase in the activity of serotonin and norepinephrine, which are two naturally occurring substances in the brain and spinal cord.

Cymbalta is in a class of medications called selective SNRIs (serotonin and norepinephrine reuptake inhibitors).

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Q. What is the difference between Brand and Generic Cymbalta?
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Q. Do I need a prescription to buy Cymbalta legally?
A. You do not need a prescription to buy Cymbalta as we work under the laws of the country we ship from. Our pharmacy does not offer legal advice. In most countries it is legal to order medicine online if the quantity in the shipment you are receiving does not exceed a 90 day supply for personal medical use and you are under the supervision of a physician. Please verify local regulations before placing an order.

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